GM 2mg/500mg Tablet
Manufacturer
Diligence Pharma
Salt Composition
Glimepiride (2mg) + Metformin (500mg)
Key Information
Short Description
GM 2mg/500mg Tablet is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Dosage Form
Tablet
Introduction
GM 2mg/500mg Tablet belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. GM 2mg/500mg Tablet is to be taken with food.
How it works
GM 2mg/500mg Tablet is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.
Quick Tips
Take it with food to lower your chance of having an upset stomach. Monitor your blood sugar level regularly while you are taking this medicine. It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as GM 2mg/500mg Tablet may cause a rare but serious condition called lactic acidosis which is an excess of lactic acid in the blood.
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Frequently asked questions
What are the recommended storage conditions for GM 2mg/500mg Tablet?
Keep this medicine in its original container, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of unused medication.
Can the use of GM 2mg/500mg Tablet lead to lactic acidosis?
Yes, the use of GM 2mg/500mg Tablet can increase the risk of lactic acidosis. It is a medical emergency that occurs when there are elevated levels of lactic acid in the blood. This condition is known as MALA (Metformin-associated lactic acidosis) and is a rare side effect linked to the use of metformin, particularly for patients with pre-existing kidney issues, older adults, or those who consume high amounts of alcohol.
What is GM 2mg/500mg Tablet?
GM 2mg/500mg Tablet contains a combination of two active ingredients: Glimepiride and Metformin. This medication is used for the treatment of type 2 diabetes mellitus (DM) in adults when taken alongside a proper diet and regular exercise. Glimepiride helps to lower blood glucose levels by increasing insulin release from the pancreas, while Metformin works by reducing glucose production in the liver and enhancing insulin sensitivity.
What are the possible side effects of GM 2mg/500mg Tablet?
Common side effects associated with the use of GM 2mg/500mg Tablet include hypoglycemia (low blood sugar), alterations in taste, nausea, abdominal discomfort, diarrhea, and headaches. Rare but serious side effects can include lactic acidosis. Long-term use may lead to vitamin B12 deficiency.
Can the use of GM 2mg/500mg Tablet cause Vitamin B12 deficiency?
Yes, long-term use of GM 2mg/500mg Tablet can lead to vitamin B12 deficiency. This is due to interference with vitamin B12 absorption in the stomach. Untreated vitamin B12 deficiency may result in anemia, nerve problems (such as tingling or numbness in hands and feet), weakness, urinary issues, changes in mental status, and difficulty maintaining balance (ataxia). To mitigate this risk, some experts recommend ensuring adequate intake of Vitamin B12 through external sources at least once a year.
Can the use of GM 2mg/500mg Tablet cause hypoglycemia?
Yes, the use of GM 2mg/500mg Tablet can cause hypoglycemia (low blood sugar levels). Common symptoms include nausea, headache, irritability, hunger, sweating, dizziness, a rapid heartbeat, and feeling anxious or shaky. This is more likely to occur if you miss meals, drink alcohol, exercise excessively, or take other antidiabetic medications concurrently. Regular blood sugar monitoring is crucial. It's advisable to always carry glucose tablets, honey, or fruit juice as quick sources of energy.
Is it safe to take alcohol while I am also taking GM 2mg/500mg Tablet?
No, combining alcohol with GM 2mg/500mg Tablet is not advisable. It can lower your blood sugar levels and increase the risk of hypoglycemia. It may also elevate the risk of lactic acidosis.
