Glyphase M2 Tablet SR
Manufacturer
Griffins Life Sciences Pvt. Ltd
Salt Composition
Glimepiride (2mg) + Metformin (500mg)
Key Information
Short Description
Glyphase M2 Tablet SR is a combination of two medicines used to treat type 2 diabetes mellitus in adults, helping to control blood sugar levels.
Dosage Form
Tablet SR
Introduction
Glyphase M2 Tablet SR belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush, or break it. Glyphase M2 Tablet SR is to be taken with food.
Safety Information
Side Effects
It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol, or if you delay or miss a meal.
Alcohol Warning
It is unsafe to consume alcohol with Glyphase M2 Tablet SR.
Breastfeeding Warning
Glyphase M2 Tablet SR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Pregnancy Warning
Glyphase M2 Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
How it works
Glyphase M2 Tablet SR is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.
Quick Tips
Monitor your blood sugar level regularly while you are taking this medicine. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Glyphase M2 Tablet SR may cause a rare but serious condition called lactic acidosis which is an excess of lactic acid in the blood.
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Frequently asked questions
What are the recommended storage conditions for Glyphase M2 Tablet SR?
Store this medicine in its original container, tightly closed, according to the instructions on the pack or label. Dispose of unused medicine properly and ensure it's not accessible to pets, children, and other individuals.
Can the use of Glyphase M2 Tablet SR lead to lactic acidosis?
Yes, Glyphase M2 Tablet SR can cause lactic acidosis, a rare but serious medical emergency characterized by increased blood lactate levels. It's associated with metformin and may be harmful for patients with kidney disease, older adults, or those who consume large amounts of alcohol. Symptoms include muscle pain, weakness, dizziness, nausea, vomiting, stomach pain, and slow heart rate. If you experience these symptoms, stop taking Glyphase M2 Tablet SR and consult your doctor immediately.
What is Glyphase M2 Tablet SR?
Glyphase M2 Tablet SR is a combination medication containing Glimepiride and Metformin. It's used to treat type 2 diabetes mellitus (DM) in adults, improving blood glucose levels when taken with a proper diet and regular exercise. Glimepiride increases insulin release from the pancreas, while metformin lowers liver glucose production and enhances insulin sensitivity. This combination is not suitable for treating type 1 DM.
What are the possible side effects of Glyphase M2 Tablet SR?
Common side effects include hypoglycemia (low blood sugar), altered taste, nausea, stomach pain, diarrhea, and headache. Rare but serious side effects may include lactic acidosis and Vitamin B12 deficiency on long-term use.
Can the use of Glyphase M2 Tablet SR lead to Vitamin B12 deficiency?
Yes, Glyphase M2 Tablet SR can cause Vitamin B12 deficiency due to interference with stomach absorption. Long-standing deficiency may result in anemia, nerve problems (tingling sensation and numbness in hands and feet), weakness, urinary issues, mental status changes, and balance difficulties (ataxia). Consult your doctor about taking supplementary Vitamin B12.
Can the use of Glyphase M2 Tablet SR cause hypoglycemia?
Yes, Glyphase M2 Tablet SR can cause hypoglycemia. Symptoms include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. Be aware that hypoglycemia may occur if you miss or delay meals, consume alcohol, over-exercise, or take other antidiabetic medicines. Regularly monitor your blood sugar levels and keep a quick source of sugar nearby.
Is it safe to take alcohol while I am also taking Glyphase M2 Tablet SR?
No, it is not recommended to consume alcohol while taking Glyphase M2 Tablet SR, as it may lower blood sugar levels and increase the risk of hypoglycemia or lactic acidosis.
