Glyphase M1 Tablet SR
Manufacturer
Griffins Life Sciences Pvt. Ltd
Salt Composition
Glimepiride (1mg) + Metformin (500mg)
Key Information
Short Description
Glyphase M1 Tablet SR is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Dosage Form
Tablet SR
Introduction
Glyphase M1 Tablet SR belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glyphase M1 Tablet SR is to be taken with food.
Safety Information
Side Effects
Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea vomiting and stomach pain as Glyphase M1 Tablet SR may cause a rare but serious condition called lactic acidosis
Alcohol Warning
It is unsafe to consume alcohol with Glyphase M1 Tablet SR.
Breastfeeding Warning
Glyphase M1 Tablet SR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Pregnancy Warning
Glyphase M1 Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
How it works
Glyphase M1 Tablet SR is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.
Quick Tips
Take it with food to lower your chance of having an upset stomach. Monitor your blood sugar level regularly while you are taking this medicine. It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
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Frequently asked questions
What are the recommended storage conditions for Glyphase M1 Tablet SR?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, and other people.
Can Glyphase M1 Tablet SR lead to lactic acidosis?
Yes, the use of Glyphase M1 Tablet SR can lead to lactic acidosis. It is a medical emergency caused by increased levels of lactic acid in the blood. This is also known as MALA (Metformin-associated lactic acidosis). It is a rare side effect associated with metformin and therefore considered harmful for patients with pre-existing kidney disease, older adults, or those who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of coldness in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain, or a slow heart rate. If you experience these symptoms, stop taking Glyphase M1 Tablet SR and consult your doctor immediately.
What is Glyphase M1 Tablet SR?
Glyphase M1 Tablet SR is a combination of two medicines: Glimepiride and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Glimepiride lowers the blood glucose level by increasing the release of insulin from the pancreas. Metformin works by lowering glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of type 1 DM.
What are the possible side effects of Glyphase M1 Tablet SR?
Like many medications, Glyphase M1 Tablet SR can have side effects. Common side effects include hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, and headache. In rare cases, it may lead to serious but less common side effects like lactic acidosis. On long-term use, it can also increase the risk of Vitamin B12 deficiency.
Can the use of Glyphase M1 Tablet SR cause Vitamin B12 deficiency?
Yes, the use of Glyphase M1 Tablet SR can cause Vitamin B12 deficiency on long-term use. It interferes with the absorption of Vitamin B12 in the stomach. If untreated, it may lead to anemia and nerve problems. Symptoms include tingling sensation and numbness in hands and feet, weakness, urinary problems, changes in mental status, and difficulty in maintaining balance (ataxia). To prevent this issue, some researchers recommend taking external sources of Vitamin B12 at least once per year.
Can the use of Glyphase M1 Tablet SR lead to hypoglycemia?
Yes, the use of Glyphase M1 Tablet SR can cause hypoglycemia (low blood sugar level). Symptoms include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. This can occur more often if you miss or delay food, drink alcohol, over-exercise, take other antidiabetic medications with it, or have a history of low blood sugar.
Is it safe to take alcohol while I am also taking Glyphase M1 Tablet SR?
No, it is not safe to take Glyphase M1 Tablet SR along with alcohol. Alcohol can lower your blood sugar levels and increase the risk of hypoglycemia.
