Glykris M 2mg/500mg Tablet SR
Manufacturer
Krishbaj India Pharmaceuticals Pvt Ltd
Salt Composition
Glimepiride (2mg) + Metformin (500mg)
Key Information
Short Description
Glykris M 2mg/500mg Tablet SR is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Dosage Form
Tablet SR
Introduction
Glykris M 2mg/500mg Tablet SR is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes. It is a combination of two medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glykris M 2mg/500mg Tablet SR is to be taken with food.
How it works
Glykris M 2mg/500mg Tablet SR is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.
Quick Tips
You have been prescribed this combination medicine as it can control blood sugar better than metformin alone. You should continue to exercise regularly eat a healthy diet and take your other diabetes medicines along with Glykris M 2mg/500mg Tablet SR. Take it with food to lower your chance of having an upset stomach. Monitor your blood sugar level regularly while you are taking this medicine. It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
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Frequently asked questions
What are the recommended storage conditions for Glykris M 2mg/500mg Tablet SR?
Keep this medicine in its original container or pack, tightly closed. Store it according to the instructions on the packaging label. Dispose of any unused medicine as per your doctor's advice. Ensure that pets, children, and other individuals do not have access to it.
Can the use of Glykris M 2mg/500mg Tablet SR lead to lactic acidosis?
Yes, the use of Glykris M 2mg/500mg Tablet SR can potentially lead to lactic acidosis. It is a medical emergency caused by an increase in lactic acid levels in the bloodstream. This condition is also known as MALA (Metformin-associated lactic acidosis). While rare, it's considered harmful for individuals with pre-existing kidney problems, elderly patients, or those consuming large amounts of alcohol. If you experience symptoms such as muscle pain, weakness, dizziness, fatigue, cold sensations in arms and legs, difficulty breathing, nausea, vomiting, stomach pain, or a slow heart rate after taking Glykris M 2mg/500mg Tablet SR, immediately stop its use and consult your doctor.
What is Glykris M 2mg/500mg Tablet SR?
Glykris M 2mg/500mg Tablet SR combines two medications: Glimepiride and Metformin. It's used for the management of type 2 diabetes mellitus (DM). This combination aids in improving blood glucose levels in adults who use it along with a balanced diet and exercise. Glimepiride lowers blood glucose levels by promoting insulin release from the pancreas. On the other hand, Metformin works by lowering glucose production in the liver and enhancing insulin sensitivity. It's not indicated for type 1 DM treatment.
What are the possible side effects of Glykris M 2mg/500mg Tablet SR?
Common side effects associated with the use of Glykris M 2mg/500mg Tablet SR include hypoglycemia (low blood sugar), altered taste, nausea, stomach pain, diarrhea, and headaches. It can also lead to serious but rare side effects such as lactic acidosis. In the long term, it can cause vitamin B12 deficiency.
Can the use of Glykris M 2mg/500mg Tablet SR lead to Vitamin B12 deficiency?
Yes, long-term use of Glykris M 2mg/500mg Tablet SR can cause vitamin B12 deficiency. This is because it interferes with the absorption of Vitamin B12 in the stomach. If untreated, this could lead to anemia and nerve problems, causing tingling sensations and numbness in hands and feet, weakness, urinary issues, altered mental status, and difficulty maintaining balance (ataxia). To prevent such complications, some healthcare professionals suggest a yearly intake of vitamin B12 from external sources.
Can the use of Glykris M 2mg/500mg Tablet SR cause hypoglycemia?
Yes, the use of Glykris M 2mg/500mg Tablet SR can lead to hypoglycemia (low blood sugar). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. This is more likely if you miss meals, drink alcohol excessively, overexercise, take other antidiabetic medication concurrently, or experience delayed food intake.
Is it safe to take alcohol while I am also taking Glykris M 2mg/500mg Tablet SR?
No, it is not advisable to consume alcohol alongside Glykris M 2mg/500mg Tablet SR. This combination can lower your blood sugar levels and increase the risk of hypoglycemia. Additionally, it may exacerbate lactic acidosis.
