Glybir Plus G2 Tablet SR
Manufacturer
Brilliant Lifesciences Pvt Ltd
Salt Composition
Glimepiride (2mg) + Metformin (500mg)
Key Information
Short Description
Glybir Plus G2 Tablet SR is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Dosage Form
Tablet SR
Introduction
Glybir Plus G2 Tablet SR belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glybir Plus G2 Tablet SR is to be taken with food.
Safety Information
Side Effects
Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea vomiting and stomach pain as Glybir Plus G2 Tablet SR may cause a rare but serious condition called lactic acidosis which is an excess of lactic acid in the blood.
Alcohol Warning
It is unsafe to consume alcohol with Glybir Plus G2 Tablet SR.
Breastfeeding Warning
Glybir Plus G2 Tablet SR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Pregnancy Warning
Glybir Plus G2 Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
How it works
Glybir Plus G2 Tablet SR is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.
Quick Tips
Take it with food to lower your chance of having an upset stomach. Monitor your blood sugar level regularly while you are taking this medicine. It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Glybir Plus G2 Tablet SR may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
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Frequently asked questions
What are the recommended storage conditions for Glybir Plus G2 Tablet SR?
Keep this medicine in its original container or pack, tightly closed. Store it according to the instructions on the label or package leaflet. Do not use an expired medicine and ensure that it is not consumed by pets, children, or others.
Can the use of Glybir Plus G2 Tablet SR lead to lactic acidosis?
Yes, the use of Glybir Plus G2 Tablet SR can potentially lead to lactic acidosis. It is a serious medical condition caused by an increase in lactic acid levels in the blood, known as Malignant Lactic Acidosis (MLA). It is related to the use of metformin and therefore, patients with pre-existing kidney issues, the elderly, or those consuming high alcohol amounts should be aware of this risk.
What is Glybir Plus G2 Tablet SR?
Glybir Plus G2 Tablet SR combines two medicines: Glimepiride and Metformin. This combination is used to treat type 2 diabetes mellitus (DM). It helps regulate blood glucose levels in adults alongside a healthy diet and regular exercise. Glimepiride increases the insulin release from the pancreas, while metformin decreases glucose production by the liver and improves insulin sensitivity.
What are the possible side effects of Glybir Plus G2 Tablet SR?
Common side effects include hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, and headaches. In rare cases, serious side effects like lactic acidosis may occur. Long-term use can also lead to Vitamin B12 deficiency.
Can the use of Glybir Plus G2 Tablet SR cause Vitamin B12 deficiency?
Yes, long-term use of Glybir Plus G2 Tablet SR can contribute to Vitamin B12 deficiency. It interferes with Vitamin B12 absorption in the stomach, which may lead to anemia and neurological problems like tingling sensations or numbness in hands and feet, weakness, urinary problems, change in mental status, and difficulty maintaining balance (ataxia). To prevent such issues, some experts suggest supplementing Vitamin B12 from external sources at least once every year.
Can the use of Glybir Plus G2 Tablet SR cause hypoglycemia?
Yes, taking Glybir Plus G2 Tablet SR can lead to hypoglycemia (low blood sugar level). Symptoms include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feelings of anxiety or shakiness. It's more likely to occur when missing meals, consuming alcohol, overexerting yourself, or taking other antidiabetic medications alongside it. Regular monitoring of your blood sugar levels is crucial. Always keep a quick source of glucose like glucose tablets, honey, or fruit juice readily available.
Is it safe to take alcohol while I am also taking Glybir Plus G2 Tablet SR?
No, it is not recommended to combine alcohol with Glybir Plus G2 Tablet SR. This combination can lower blood sugar levels and increase the risk of hypoglycemia. It may also elevate the chances of lactic acidosis.
