Gluconorm-Z XR 60 Tablet
Manufacturer
Lupin Ltd
Salt Composition
Metformin (500mg) + Gliclazide (60mg)
Key Information
Short Description
Gluconorm-Z XR 60 Tablet is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Dosage Form
Tablet MR
Introduction
Gluconorm-Z XR 60 Tablet belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Gluconorm-Z XR 60 Tablet is to be taken with food.
Safety Information
Side Effects
No common side effects listed.
Alcohol Warning
It is unsafe to consume alcohol with Gluconorm-Z XR 60 Tablet.
Breastfeeding Warning
Gluconorm-Z XR 60 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Pregnancy Warning
Gluconorm-Z XR 60 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
How it works
Gluconorm-Z XR 60 Tablet is a combination of two antidiabetic medicines: Gliclazide and Metformin.
Quick Tips
Monitor your blood sugar level regularly while you are taking this medicine. It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Gluconorm-Z XR 60 Tablet may cause a rare but serious condition called lactic acidosis which is an excess of lactic acid in the blood.
Frequently asked questions
What is Gluconorm-Z XR 60 Tablet?
Gluconorm-Z XR 60 Tablet is a combination medication consisting of two active ingredients: Gliclazide and Metformin. This medication is used to treat type 2 diabetes mellitus (DM) in adults. It helps improve blood glucose levels when taken alongside a proper diet and regular exercise. Gliclazide works by increasing the release of insulin from the pancreas, while Metformin lowers glucose production in the liver and improves insulin sensitivity.
What are the possible side effects of Gluconorm-Z XR 60 Tablet?
Common side effects associated with Gluconorm-Z XR 60 Tablet include hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory tract infection. Rare but serious side effects include lactic acidosis and vitamin B12 deficiency, especially when taken long-term.
Can the use of Gluconorm-Z XR 60 Tablet cause hypoglycemia?
Yes, using Gluconorm-Z XR 60 Tablet can lead to hypoglycemia. Symptoms include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. This risk is higher if you skip or delay meals, drink alcohol, over-exercise, or take other antidiabetic medications alongside Gluconorm-Z XR 60 Tablet. Regular blood sugar level monitoring is crucial.
Can the use of Gluconorm-Z XR 60 Tablet cause lactic acidosis?
Yes, using Gluconorm-Z XR 60 Tablet can lead to lactic acidosis, a medical emergency. This condition is characterized by increased levels of lactic acid in the blood and is associated with Metformin use. It's more likely in patients with kidney disease, older adults, or those who consume large amounts of alcohol. Symptoms include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty breathing, nausea, vomiting, stomach pain, or slow heart rate.
Can the use of Gluconorm-Z XR 60 Tablet lead to Vitamin B12 deficiency?
Yes, using Gluconorm-Z XR 60 Tablet can cause vitamin B12 deficiency on long-term use. This occurs because the medication interferes with the absorption of vitamin B12 in the stomach. Untreated deficiency may result in anemia and nerve problems, manifesting as tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status, and difficulty maintaining balance (ataxia). Some researchers recommend taking vitamin B12 supplements at least once a year to prevent such issues.
Are there any specific conditions in which Gluconorm-Z XR 60 Tablet should not be taken?
Yes, patients with known allergies to the components or excipients of this medication should avoid using Gluconorm-Z XR 60 Tablet. It's also contraindicated for those with moderate to severe kidney disease or underlying metabolic acidosis, including diabetic ketoacidosis.
Is it safe to take alcohol while taking Gluconorm-Z XR 60 Tablet?
No, consuming alcohol alongside Gluconorm-Z XR 60 Tablet is not recommended. Alcohol may lower blood sugar levels (hypoglycemia) and increase the risk of lactic acidosis.
