Gliris-M 2 Tablet PR
Manufacturer
Bioiris Pharmaceuticals Pvt Ltd
Salt Composition
Glimepiride (2mg) + Metformin (500mg)
Key Information
Short Description
Gliris-M 2 Tablet PR is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Dosage Form
Tablet PR
Introduction
Gliris-M 2 Tablet PR belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Directions for Use
Use it as advised by your doctor or check the label for directions before use. Gliris-M 2 Tablet PR is to be taken with food.
Safety Information
Side Effects
It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Alcohol Warning
It is unsafe to consume alcohol with Gliris-M 2 Tablet PR.
Breastfeeding Warning
Gliris-M 2 Tablet PR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Pregnancy Warning
Gliris-M 2 Tablet PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
How it works
Gliris-M 2 Tablet PR is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.
Quick Tips
Take it with food to lower your chance of having an upset stomach. Monitor your blood sugar level regularly while you are taking this medicine. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Gliris-M 2 Tablet PR may cause a rare but serious condition called lactic acidosis which is an excess of lactic acid in the blood.
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Frequently asked questions
What are the recommended storage conditions for Gliris-M 2 Tablet PR?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, and other people.
Can the use of Gliris-M 2 Tablet PR lead to lactic acidosis?
Yes, the use of Gliris-M 2 Tablet PR can lead to lactic acidosis. It is a medical emergency caused by increased levels of lactic acid in the blood. This condition is also known as MALA (Metformin-associated Lactic acidosis). While rare, it is considered harmful for patients with underlying kidney disease, elderly individuals, or those who consume large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, a feeling of cold in the arms and legs, difficulty breathing, nausea, vomiting, stomach pain, or a slow heart rate. If you experience these symptoms, discontinue Gliris-M 2 Tablet PR immediately and consult your doctor.
What is Gliris-M 2 Tablet PR?
Gliris-M 2 Tablet PR is a combination of two medicines: Glimepiride and Metformin. This medication is used for the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken with proper diet and exercise. Glimepiride lowers blood glucose by increasing insulin release from the pancreas. Metformin works by lowering glucose production in the liver and enhancing insulin sensitivity. This combination is not indicated for the treatment of type 1 DM.
What are the possible side effects of Gliris-M 2 Tablet PR?
The use of Gliris-M 2 Tablet PR can cause common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, and headaches. It may also lead to rare but serious side effects like lactic acidosis. Long-term use might result in Vitamin B12 deficiency.
Can the use of Gliris-M 2 Tablet PR cause Vitamin B12 deficiency?
Yes, long-term use of Gliris-M 2 Tablet PR can lead to Vitamin B12 deficiency. It interferes with the absorption of Vitamin B12 in the stomach. If untreated, it may result in anemia and nerve problems, causing tingling sensations in hands and feet, weakness, urinary problems, a change in mental status, and difficulty maintaining balance (ataxia). To prevent such issues, researchers suggest taking external sources of Vitamin B12 at least once a year.
Can the use of Gliris-M 2 Tablet PR lead to hypoglycemia?
Yes, the use of Gliris-M 2 Tablet PR can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. It can happen more often if you miss or delay meals, drink alcohol, over-exercise, or take other antidiabetic medications with it. Regular monitoring of blood sugar levels is important. Always keep a quick source of sugar like glucose tablets, honey, or fruit juice readily available.
Is it safe to take alcohol while I am also taking Gliris-M 2 Tablet PR?
No, it is not safe to take Gliris-M 2 Tablet PR along with alcohol. Combining these can lower your blood sugar levels and result in hypoglycemia or increase the risk of lactic acidosis.
