

Glipkul-M 2 Tablet SR
Manufacturer
Akul Pharma
Salt Composition
Glimepiride (2mg) + Metformin (500mg)
Key Information
Short Description
Glipkul-M 2 Tablet SR is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Dosage Form
Tablet SR
Introduction
Glipkul-M 2 Tablet SR belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glipkul-M 2 Tablet SR is to be taken with food.
How it works
Glipkul-M 2 Tablet SR is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.
Quick Tips
Take it with food to lower your chance of having an upset stomach. Monitor your blood sugar level regularly while you are taking this medicine. It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Glipkul-M 2 Tablet SR may cause a rare but serious condition called lactic acidosis which is an excess of lactic acid in the blood.
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Frequently asked questions
What are the recommended storage conditions for Glipkul-M 2 Tablet SR?
Keep this medicine in its container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the packaging label. Dispose of unused medication. Do not give this medication to pets, children, or other people.
Can the use of Glipkul-M 2 Tablet SR lead to lactic acidosis?
Yes, using Glipkul-M 2 Tablet SR can increase the risk of lactic acidosis. This is a rare but serious side effect caused by an increase in lactic acid levels in the blood. It is also known as MALA (Metformin-associated lactic acidosis). It may be more likely to occur if a patient has underlying kidney disease, is elderly, or consumes large amounts of alcohol. Symptoms include muscle pain or weakness, dizziness, tiredness, feeling cold in arms and legs, difficulty breathing, nausea, vomiting, stomach pain, or a slow heart rate. If you experience any of these symptoms, discontinue Glipkul-M 2 Tablet SR immediately and contact your doctor.
What is Glipkul-M 2 Tablet SR?
Glipkul-M 2 Tablet SR contains two medications: Glimepiride and Metformin. This combination is used to treat type 2 diabetes mellitus (DM). It improves blood sugar levels in adults when taken with a proper diet and regular exercise. Glimepiride lowers blood glucose levels by increasing insulin release from the pancreas. Metformin works by lowering glucose production in the liver and improving insulin sensitivity. This combination is not used to treat type 1 DM.
What are the possible side effects of Glipkul-M 2 Tablet SR?
Common side effects of Glipkul-M 2 Tablet SR include hypoglycemia (low blood sugar), changes in taste, nausea, stomach pain, diarrhea, and headache. It can also lead to serious but rare side effects such as lactic acidosis. Long-term use may increase the risk of Vitamin B12 deficiency.
Can the use of Glipkul-M 2 Tablet SR cause Vitamin B12 deficiency?
Yes, long-term use of Glipkul-M 2 Tablet SR can lead to Vitamin B12 deficiency. It interferes with the absorption of Vitamin B12 in the stomach. If not treated properly, it could result in anemia and nerve problems, which may cause tingling sensations and numbness in hands and feet, weakness, urinary problems, changes in mental status, and difficulty maintaining balance (ataxia). To avoid these issues, consider consuming a source of Vitamin B12 from outside sources at least once per year.
Can the use of Glipkul-M 2 Tablet SR cause hypoglycemia?
Yes, Glipkul-M 2 Tablet SR can cause hypoglycemia (low blood sugar level). Symptoms include nausea, headache, irritability, hunger, sweating, dizziness, a fast heart rate, and feeling anxious or shaky. This is more likely to occur when you miss meals, drink alcohol, over-exercise, or take other antidiabetic medications with it. Regular blood sugar monitoring is essential for those taking this medication.
Is it safe to take alcohol while I am also taking Glipkul-M 2 Tablet SR?
No, it is not safe to take alcohol while using Glipkul-M 2 Tablet SR. This combination can lower your blood sugar levels and increase the risk of hypoglycemia. It may also contribute to an increased risk of lactic acidosis.