Glimple M 1mg/500mg Tablet
Manufacturer
Plena Remedies
Salt Composition
Glimepiride (1mg) + Metformin (500mg)
Key Information
Short Description
Glimple M 1mg/500mg Tablet is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Dosage Form
Tablet
Introduction
Glimple M 1mg/500mg Tablet belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glimple M 1mg/500mg Tablet is to be taken with food.
Safety Information
Side Effects
No common side effects listed.
Alcohol Warning
It is unsafe to consume alcohol with Glimple M 1mg/500mg Tablet.
Breastfeeding Warning
Glimple M 1mg/500mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Pregnancy Warning
Glimple M 1mg/500mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
How it works
Glimple M 1mg/500mg Tablet is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.
Quick Tips
You should continue to exercise regularly eat a healthy diet and take your other diabetes medicines along with Glimple M 1mg/500mg Tablet. Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
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Frequently asked questions
What are the recommended storage conditions for Glimple M 1mg/500mg Tablet?
Store Glimple M 1mg/500mg Tablet in the original container or pack it came in, tightly sealed. Refer to the label or packaging instructions on how to store this medication. Do not share it with others or allow pets, children, or other people to access it.
Can the use of Glimple M 1mg/500mg Tablet lead to lactic acidosis?
Yes, using Glimple M 1mg/500mg Tablet can increase the risk of lactic acidosis. This is a medical emergency that occurs when there is an accumulation of lactic acid in the blood. It's also known as MALA (Metformin-associated Lactic acidosis). It's a rare side effect associated with metformin and poses potential harm for patients with pre-existing kidney disease, elderly individuals, or those who consume large amounts of alcohol. Symptoms of lactic acidosis can include muscle pain or weakness, dizziness, tiredness, feeling cold in arms and legs, difficulty breathing, nausea, vomiting, stomach pain, or slow heart rate. If you experience these symptoms, discontinue Glimple M 1mg/500mg Tablet immediately and seek medical attention.
What is Glimple M 1mg/500mg Tablet?
Glimple M 1mg/500mg Tablet contains Glimepiride and Metformin in a combination dosage. This medication is used to treat type 2 diabetes mellitus (DM). It helps control blood glucose levels by improving insulin action in adults. Glimepiride increases insulin release from the pancreas, while Metformin works by decreasing glucose production in the liver and improving insulin sensitivity. This specific combination of medicines is not suitable for treating type 1 diabetes.
What are the possible side effects of Glimple M 1mg/500mg Tablet?
Glimple M 1mg/500mg Tablet may cause common side effects like hypoglycemia (low blood sugar), altered taste, nausea, stomach pain, diarrhea, and headache. It can also lead to serious but rare side effects such as lactic acidosis. In the long-term use of this medication, it may result in vitamin B12 deficiency.
Can the use of Glimple M 1mg/500mg Tablet cause vitamin B12 deficiency?
Yes, prolonged use of Glimple M 1mg/500mg Tablet can lead to vitamin B12 deficiency. This is because it interferes with the absorption of vitamin B12 in the stomach. If left untreated, this may result in anemia and nerve problems, which include tingling or numbness in hands and feet, weakness, urinary problems, changes in mental status, and difficulties maintaining balance (ataxia). To prevent such issues, supplemental Vitamin B12 intake through food sources is recommended at least once a year.
Can the use of Glimple M 1mg/500mg Tablet cause hypoglycemia?
Yes, using Glimple M 1mg/500mg Tablet can lead to hypoglycemia (low blood sugar level). Symptoms include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. This risk is higher when you miss meals, drink alcohol, over-exercise, take other antidiabetic medications concurrently, or delay food intake. Regular blood glucose monitoring is crucial. Always carry a quick source of sugar like glucose tablets, honey, or fruit juice for immediate use.
Is it safe to drink alcohol while I'm taking Glimple M 1mg/500mg Tablet?
No, drinking alcohol is not recommended in combination with Glimple M 1mg/500mg Tablet. It can lower blood sugar levels and increase the risk of hypoglycemia. Additionally, it may lead to an increased incidence of lactic acidosis.
