Glibest M 1mg/500mg Tablet SR
Manufacturer
Best Biotech
Salt Composition
Glimepiride (1mg) + Metformin (500mg)
Key Information
Short Description
Glibest M 1mg/500mg Tablet SR is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Dosage Form
Tablet SR
Introduction
Glibest M 1mg/500mg Tablet SR belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glibest M 1mg/500mg Tablet SR is to be taken with food.
How it works
Glibest M 1mg/500mg Tablet SR is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.
Quick Tips
You have been prescribed this combination medicine as it can control blood sugar better than metformin alone. Continue to exercise regularly Eat a healthy diet Take your other diabetes medicines along with Glibest M 1mg/500mg Tablet SR. Take it with food to lower your chance of having an upset stomach.
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Frequently asked questions
What are the recommended storage conditions for Glibest M 1mg/500mg Tablet SR?
Keep this medicine in the container or pack it came in, tightly closed. Store according to the instructions mentioned on the pack or label. Dispose of unused medicine. Make sure it is not consumed by pets, children, and other people.
Can the use of Glibest M 1mg/500mg Tablet SR lead to lactic acidosis?
Yes, Glibest M 1mg/500mg Tablet SR can cause lactic acidosis. It is a medical emergency caused by increased levels of lactic acid in the blood. It's also known as MALA (Metformin-associated lactic acidosis). This rare side effect is associated with metformin use and therefore can be harmful for patients with underlying kidney disease, older adults, or those consuming large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feelings of coldness in the arms and legs, difficulty breathing, nausea, vomiting, stomach pain, or slow heart rate. If experiencing these symptoms, stop Glibest M 1mg/500mg Tablet SR and consult your doctor immediately.
What is Glibest M 1mg/500mg Tablet SR?
Glibest M 1mg/500mg Tablet SR is a combination of two medicines: Glimepiride and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Glimepiride lowers blood glucose by increasing insulin release from the pancreas, while Metformin works by reducing glucose production in the liver and improving insulin sensitivity. This combination is not indicated for treating type 1 DM.
What are the possible side effects of Glibest M 1mg/500mg Tablet SR?
Possible side effects of Glibest M 1mg/500mg Tablet SR include hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, and headache. Rare but serious side effects may occur, such as lactic acidosis. Long-term use can also lead to Vitamin B12 deficiency.
Can the use of Glibest M 1mg/500mg Tablet SR cause Vitamin B12 deficiency?
Yes, long-term use of Glibest M 1mg/500mg Tablet SR can lead to Vitamin B12 deficiency. This is due to its impact on the absorption of Vitamin B12 in the stomach. If left untreated, it may cause anemia and nerve problems, leading to tingling sensations in hands and feet, weakness, urinary problems, changes in mental status, and difficulty maintaining balance (ataxia). To avoid these complications, consider supplementing with Vitamin B12 from outside sources at least once a year.
Can the use of Glibest M 1mg/500mg Tablet SR cause hypoglycemia?
Yes, Glibest M 1mg/500mg Tablet SR can lead to hypoglycemia (low blood sugar level). Symptoms include nausea, headache, irritability, hunger, sweating, dizziness, a fast heartbeat, and feelings of anxiety or shakiness. This may happen more frequently if you miss or delay meals, drink alcohol, exercise excessively, or take other antidiabetic medications together with it. Regular blood sugar monitoring is essential. Always keep a quick source of sugar like glucose tablets, honey, or fruit juice readily available.
Is it safe to take alcohol while I am also taking Glibest M 1mg/500mg Tablet SR?
No, consuming alcohol with Glibest M 1mg/500mg Tablet SR is not recommended as this can lower blood sugar levels and increase the risk of hypoglycemia. It may also heighten the likelihood of lactic acidosis.
