


Glavin-M1 Tablet
Manufacturer
Avin Pharma
Salt Composition
Glimepiride (1mg) + Metformin (500mg)
Key Information
Short Description
Glavin-M1 Tablet is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Dosage Form
Tablet
Introduction
Glavin-M1 Tablet belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glavin-M1 Tablet is to be taken with food.
Safety Information
Side Effects
It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Alcohol Warning
It is unsafe to consume alcohol with Glavin-M1 Tablet.
Breastfeeding Warning
Glavin-M1 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Pregnancy Warning
Glavin-M1 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
How it works
Glavin-M1 Tablet is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.
Quick Tips
Take it with food to lower your chance of having an upset stomach. Monitor your blood sugar level regularly while you are taking this medicine. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Glavin-M1 Tablet may cause a rare but serious condition called lactic acidosis which is an excess of lactic acid in the blood.
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Frequently asked questions
What are the recommended storage conditions for Glavin-M1 Tablet?
Store Glavin-M1 Tablet in its original container, tightly closed, and follow the storage instructions provided on the packaging or label. Dispose of any unused medication and ensure it is not accessible to pets, children, or other individuals.
Can the use of Glavin-M1 Tablet lead to lactic acidosis?
Yes, the use of Glavin-M1 Tablet can cause lactic acidosis, a rare but serious medical emergency characterized by elevated blood lactate levels. This condition is more likely to occur in patients with underlying kidney disease, older adults, or those who consume large amounts of alcohol. Symptoms may include muscle pain or weakness, dizziness, fatigue, cold intolerance, shortness of breath, nausea, vomiting, abdominal pain, or slow heart rate. If you experience these symptoms, discontinue Glavin-M1 Tablet and consult your doctor immediately.
What is Glavin-M1 Tablet?
Glavin-M1 Tablet is a combination medication containing glimepiride and metformin. It is used to treat type 2 diabetes mellitus (DM) in adults, in conjunction with a proper diet and regular exercise. Glimepiride increases insulin release from the pancreas, while metformin reduces glucose production in the liver and improves insulin sensitivity. This combination is not suitable for the treatment of type 1 DM.
What are the possible side effects of Glavin-M1 Tablet?
Common side effects of Glavin-M1 Tablet include hypoglycemia (low blood sugar), altered taste, nausea, stomach pain, diarrhea, and headache. Rare but serious side effects may include lactic acidosis. Long-term use can also lead to Vitamin B12 deficiency, which may cause anemia, nerve problems, and symptoms such as tingling sensations, numbness, weakness, urinary issues, changes in mental status, and balance difficulties.
Can the use of Glavin-M1 Tablet lead to Vitamin B12 deficiency?
Yes, the use of Glavin-M1 Tablet can cause Vitamin B12 deficiency, particularly with long-term use. This is because metformin can interfere with Vitamin B12 absorption in the stomach. Untreated deficiency may lead to anemia, nerve problems, and symptoms such as tingling sensations, numbness, weakness, urinary issues, changes in mental status, and balance difficulties. To minimize this risk, consider taking Vitamin B12 supplements at least once a year.
Can the use of Glavin-M1 Tablet cause hypoglycemia?
Yes, Glavin-M1 Tablet can cause hypoglycemia (low blood sugar). Symptoms may include nausea, headache, irritability, hunger, sweating, dizziness, rapid heart rate, and feelings of anxiety or shakiness. This is more likely to occur if you miss or delay meals, consume alcohol, engage in excessive exercise, or take other antidiabetic medications. Regularly monitor your blood sugar levels and keep a quick source of sugar, such as glucose tablets, honey, or fruit juice, readily available.
Is it safe to take alcohol while I am also taking Glavin-M1 Tablet?
No, it is not recommended to consume alcohol while taking Glavin-M1 Tablet, as it may lower your blood sugar levels and increase the risk of hypoglycemia and lactic acidosis.