Glador M2 Tablet
Manufacturer
Lupin Ltd
Salt Composition
Glimepiride (2mg) + Metformin (500mg)
Key Information
Short Description
Glador M2 Tablet PR is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Dosage Form
Tablet PR
Introduction
Glador M2 Tablet PR belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Directions for Use
Use it as advised by your doctor or check the label for directions before use. Glador M2 Tablet PR is to be taken with food.
Safety Information
Side Effects
It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Alcohol Warning
It is unsafe to consume alcohol with Glador M2 Tablet PR.
Breastfeeding Warning
Glador M2 Tablet PR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Pregnancy Warning
Glador M2 Tablet PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
How it works
Glador M2 Tablet PR is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.
Quick Tips
Take it with food to lower your chance of having an upset stomach. Monitor your blood sugar level regularly while you are taking this medicine. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Glador M2 Tablet PR may cause a rare but serious condition called lactic acidosis which is an excess of lactic acid in the blood.
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Frequently asked questions
What are the recommended storage conditions for Glador M2 Tablet PR?
Keep this medicine in its original container or package, tightly sealed. Store it according to the instructions on the packaging label. Do not consume any unused medication. Ensure that pets, children and other individuals do not have access to it.
Can the use of Glador M2 Tablet PR lead to lactic acidosis?
Yes, the use of Glador M2 Tablet PR can potentially cause lactic acidosis. This is a medical emergency that arises from increased levels of lactic acid in the blood. It is also known as MALA (Metformin-associated lactic acidosis). It is a rare side effect associated with metformin and may pose risks for individuals with underlying kidney disease, elderly patients, or those who consume large amounts of alcohol. Symptoms of lactic acidosis can include muscle pain, weakness, dizziness, fatigue, cold sensations in arms and legs, shortness of breath, nausea, vomiting, stomach pain, or a slow heart rate. If you experience these symptoms, stop taking Glador M2 Tablet PR and consult your doctor immediately.
What is Glador M2 Tablet PR?
Glador M2 Tablet PR is a combination of two medicines: Glimepiride and Metformin. This medication is used to treat type 2 diabetes mellitus (DM). It helps improve blood glucose levels in adults when used in conjunction with proper diet and regular exercise. Glimepiride lowers blood glucose by increasing insulin release from the pancreas, while metformin reduces glucose production by the liver and enhances insulin sensitivity. It is not indicated for the treatment of type 1 DM.
What are possible side effects of Glador M2 Tablet PR?
Glador M2 Tablet PR may cause common side effects, such as hypoglycemia (low blood sugar level), changes in taste perception, nausea, stomach pain, diarrhea, and headache. It can also result in rare serious side effects like lactic acidosis. Long-term use may increase the risk of Vitamin B12 deficiency.
Can Glador M2 Tablet PR cause Vitamin B12 deficiency?
Yes, long-term use of Glador M2 Tablet PR can lead to Vitamin B12 deficiency. This occurs because the medication interferes with Vitamin B12 absorption in the stomach. If untreated, it could result in anemia and nerve problems. Symptoms include tingling or numbness in hands and feet, weakness, urinary issues, changes in mental status, and difficulty maintaining balance (ataxia). To mitigate this risk, some experts suggest consuming external sources of Vitamin B12 at least once a year.
Can Glador M2 Tablet PR cause hypoglycemia?
Yes, the use of Glador M2 Tablet PR can result in hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, a rapid heart rate, and feelings of anxiety or shakiness. This may be more likely to occur if you miss meals, consume alcohol, exercise excessively, or take other antidiabetic medications simultaneously with Glador M2 Tablet PR. Therefore, regular blood sugar monitoring is crucial.
Is it safe to drink alcohol while taking Glador M2 Tablet PR?
No, consuming alcohol while on Glador M2 Tablet PR is not recommended as it may cause a drop in blood sugar levels and increase the risk of hypoglycemia. Additionally, it can heighten the likelihood of lactic acidosis.
