Estimet G 2mg/500mg Tablet
Manufacturer
Grefith Life Sciences Pvt Ltd
Salt Composition
Glimepiride (2mg) + Metformin (500mg)
Key Information
Short Description
Estimet G 2mg/500mg Tablet is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Dosage Form
Tablet
Introduction
Estimet G 2mg/500mg Tablet belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Estimet G 2mg/500mg Tablet is to be taken with food.
Safety Information
Side Effects
Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea vomiting and stomach pain as Estimet G 2mg/500mg Tablet may cause a rare but serious condition called lactic acidosis which is an excess of lactic acid in the blood.
Alcohol Warning
It is unsafe to consume alcohol with Estimet G 2mg/500mg Tablet.
Breastfeeding Warning
Estimet G 2mg/500mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Pregnancy Warning
Estimet G 2mg/500mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
How it works
Estimet G 2mg/500mg Tablet is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.
Quick Tips
Take it with food to lower your chance of having an upset stomach. Monitor your blood sugar level regularly while you are taking this medicine. It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
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Frequently asked questions
What are the recommended storage conditions for Estimet G 2mg/500mg Tablet?
Keep this medicine in its original container or pack, tightly closed. Store it according to the instructions on the package label. Do not allow pets, children, or other people to access the medication.
Can the use of Estimet G 2mg/500mg Tablet lead to lactic acidosis?
Yes, using Estimet G 2mg/500mg Tablet can increase the risk of lactic acidosis. It's a rare side effect associated with metformin, and it may be harmful for patients with underlying kidney disease, elderly patients or those consuming large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling cold in arms and legs, difficulty breathing, nausea, vomiting, stomach pain, or a slow heart rate. If you experience these symptoms, stop using Estimet G 2mg/500mg Tablet and consult your doctor immediately.
What is Estimet G 2mg/500mg Tablet?
Estimet G 2mg/500mg Tablet is a combination of two active ingredients: Glimepiride and Metformin. It's used to treat type 2 diabetes mellitus (DM). This medication helps lower blood glucose levels in adults when taken alongside proper diet and exercise. Glimepiride increases insulin release from the pancreas, while Metformin reduces glucose production in the liver and improves insulin sensitivity. This combination is not suitable for treating Type 1 DM.
What are the possible side effects of Estimet G 2mg/500mg Tablet?
Possible side effects include hypoglycemia (low blood sugar), altered taste, nausea, stomach pain, diarrhea, and headaches. It can also lead to lactic acidosis in rare cases, and long-term use can cause Vitamin B12 deficiency.
Can the use of Estimet G 2mg/500mg Tablet lead to Vitamin B12 deficiency?
Yes, prolonged use of Estimet G 2mg/500mg Tablet can cause vitamin B12 deficiency. This occurs because it interferes with the absorption of vitamin B12 in the stomach. If left untreated, it may result in anemia and nerve problems. Symptoms include tingling sensation and numbness in hands and feet, weakness, urinary problems, changes in mental status, and difficulty maintaining balance (ataxia). To mitigate these effects, some experts recommend taking a Vitamin B12 supplement at least once per year.
Can the use of Estimet G 2mg/500mg Tablet cause hypoglycemia?
Yes, using Estimet G 2mg/500mg Tablet can cause hypoglycemia (low blood sugar). Common symptoms include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. This is more likely if you miss meals, drink alcohol, over-exercise, or use other antidiabetic medications simultaneously.
Is it safe to take alcohol while I am also taking Estimet G 2mg/500mg Tablet?
No, combining alcohol with Estimet G 2mg/500mg Tablet is not recommended as it may lower blood sugar levels and increase the risk of hypoglycemia. It can also contribute to lactic acidosis.
