


Dermotrex 7.5mg Tablet
Manufacturer
East West Pharma
Salt Composition
Methotrexate (7.5mg)
Key Information
Short Description
Dermotrex 7.5mg Tablet is a medicine used for treatment of cancer in various parts of the body, rheumatoid arthritis, severe and uncontrolled psoriasis, and Crohn's disease.
Dosage Form
Tablet
Introduction
Dermotrex 7.5mg Tablet may be used alone or in combination with other medicines. You should take it exactly as your doctor has advised. Taking too much of it can cause serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid consumption of alcohol while taking this medicine as it may increase your risk of liver damage. The most common side effects of this medicine are ulcerative stomatitis, hair loss, low blood cell count, increased liver enzymes, nausea, and abdominal distress. Your doctor may advise you to take folic acid to reduce some of these. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. This medicine may lower your ability to fight infections and lead to problems with your blood, liver, or kidneys. Your doctor may perform several tests such as blood tests, X-rays, and physical examinations both before and during treatment with this medicine to check for these.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush, or break it. Dermotrex 7.5mg Tablet may be taken with or without food but it is better to take it at a fixed time.
How it works
Dermotrex 7.5mg Tablet inhibits enzymes (dihydrofolate reductase), prevents cell division and leads to anti-inflammatory actions. Dermotrex 7.5mg Tablet kills cancer cells by preventing them from making DNA. Dermotrex 7.5mg Tablet can help control psoriasis by retarding the production of skin cells and suppressing inflammation. Dermotrex 7.5mg Tablet may treat rheumatoid arthritis by suppressing the immune system, preventing it from attacking the body's cells. This helps reduce the inflammation that causes swollen and stiff joints in rheumatoid arthritis or damage to bowel in Crohn's disease.
Quick Tips
Drink plenty of liquids to stay hydrated while taking this medication. Take folic acid if advised by your doctor. This will help lessen the side effects of this medicine. It may take from weeks to months for Dermotrex 7.5mg Tablet to work. Keep taking the medication as prescribed. Your doctor may get regular blood test done to monitor your kidney function, liver function, and level of blood cells in your blood. Avoid drinking alcohol while taking this medicine as it may increase the risk of side effects. It can be harmful to an unborn baby. Avoid pregnancy for at least 6 months after your last dose.
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Frequently asked questions
Can Dermotrex 7.5mg Tablet cause mouth ulcers?
Yes, Dermotrex 7.5mg Tablet may cause a sore mouth and ulcers as side effects in some patients. Taking folic acid with this medication may help reduce the severity of these ulcers. It's important to discuss reducing the dosage with your doctor, which might further aid in minimizing ulcers.
Why must I take folic acid with Dermotrex 7.5mg Tablet?
Folic acid plays a crucial role in cell growth and development, and Dermotrex 7.5mg Tablet depletes the body's folic acid levels. Combining this medication with folic acid can help mitigate side effects like mouth ulcers, hair loss, nausea, heartburn, abdominal pain, fatigue, anemia, and liver problems.
Why do I need regular blood tests while taking Dermotrex 7.5mg Tablet?
Regular blood tests are essential to monitor your body's response to Dermotrex 7.5mg Tablet and assess for any potential side effects. They help check liver function and assess your blood cell counts (white blood cells, red blood cells, and platelets). Your doctor might order additional tests based on the results.
Can Dermotrex 7.5mg Tablet increase susceptibility to infections?
Dermotrex 7.5mg Tablet may weaken your immune system, potentially increasing your vulnerability to infections. There have been rare reports of serious lung infections associated with this medication. If you currently have an active infection, it's crucial to use Dermotrex 7.5mg Tablet with extreme caution.
Can Dermotrex 7.5mg Tablet affect fertility?
Yes, Dermotrex 7.5mg Tablet can impact both male and female fertility by decreasing sperm count in men and causing menstrual irregularities in women. These effects are generally reversible upon stopping the medication. However, it's important to discuss potential risks with your doctor before conception.
What should I do if I am planning to become pregnant while my husband is taking Dermotrex 7.5mg Tablet?
It's advised to postpone pregnancy until the medication is discontinued for a minimum of three months. If you are already pregnant, consult with your doctor immediately and avoid any further use of Dermotrex 7.5mg Tablet.