Dargen 40 Injection
Manufacturer
Lupin Ltd
Salt Composition
Darbepoetin Alfa (40mcg)
Key Information
Short Description
Dargen 40 Injection is used to treat anemia caused by chronic kidney disease or chemotherapy by stimulating the bone marrow to produce more red blood cells.
Dosage Form
Injection
Introduction
Dargen 40 Injection is a medicine that needs to be used with utmost care because it can lead to serious side effects. It is important that you seek treatment from a doctor who is experienced in providing this medical therapy. You should follow all the directions of the doctor strictly. It is given under the supervision of a healthcare professional. Common side effects include abdominal pain, high blood pressure, rash, injection site pain, breathlessness, cough, and peripheral edema. Inform your doctor if there are symptoms of very high blood pressure such as severe headache, problems with your eyesight, nausea, vomiting, or fits (seizures). Your doctor may get your blood tests done regularly to monitor the levels of salts (electrolytes such as potassium), hemoglobin, and blood cells in your blood. You should stop taking it and consult with a doctor if you develop shortness of breath or skin rash. Before taking Dargen 40 Injection, tell your doctor if you have heart disease, high blood pressure, or have had a seizure or stroke. If you are pregnant or breastfeeding, or plan to become pregnant or breastfeed, consult your doctor to make sure it is safe for you.
Directions for Use
Your doctor or nurse will give you this medicine. Kindly do not self-administer.
How it works
Dargen 40 Injection is an erythropoiesis-stimulating agent (ESA). It works by stimulating the bone marrow (soft tissue inside the bones which produces red blood cells) to produce more red blood cells.
Quick Tips
Dargen 40 Injection helps in the treatment of anemia that may have occurred due to chronic kidney disease or cancer chemotherapy. It is given as a single injection under your skin It can be given intravenously. Your doctor may get your blood tests done regularly to monitor the levels of hemoglobin, blood cells, in your blood. Stop taking Dargen 40 Injection and inform your doctor if you develop shortness of breath or skin rash.
Frequently asked questions
How long does it take for Dargen 40 Injection to start working?
You may begin to see an increase in red blood cell count (hemoglobin levels) within 2-6 weeks of starting Dargen 40 Injection. However, if you have any questions or concerns, please consult your healthcare provider.
Is Dargen 40 Injection safe to use?
Dargen 40 Injection is a potent medication that carries the risk of serious side effects and even potential death. It's crucial to receive expert guidance from your healthcare provider regarding its use. Always adhere to your doctor's instructions strictly.
Besides PRCA, are there other reasons I might not respond to Dargen 40 Injection?
You may not experience improvement with Dargen 40 Injection if you have iron, folic acid, or vitamin B12 deficiencies. It's important to address these deficiencies before continuing the treatment. Other possible reasons for not responding include bleeding, infections, inflammation, and bone marrow fibrosis. Please consult your doctor for further clarification.
Can Dargen 40 Injection be used in children?
Dargen 40 Injection is prescribed to treat anemia caused by chronic kidney disease in children who are at least one year old. Its efficacy and potential side effects in children are similar to adults, but consult your healthcare provider if you have any uncertainties.
Does Dargen 40 Injection affect blood pressure?
Yes, Dargen 40 Injection can impact blood pressure. Closely monitoring blood pressure is necessary during initial therapy with Dargen 40 Injection, particularly for those with pre-existing high blood pressure. Your doctor may adjust the dosage or discontinue treatment if your blood pressure proves difficult to manage.
Who should not take Dargen 40 Injection?
It is crucial to avoid using Dargen 40 Injection if you have: cancer that has not been prescribed by a doctor (and consult your doctor first), uncontrolled hypertension (high blood pressure), or a history of anemia (pure red cell aplasia) which develops after starting Dargen 40 Injection or other erythropoiesis-stimulating agents. Additionally, patients with a known history of severe allergic reactions to Dargen 40 Injection should not use this medication.
