Biosulin N 40IU Injection
Manufacturer
Innova Life Sciences Private Limited
Salt Composition
Insulin Isophane (40IU)
Key Information
Short Description
Biosulin N 40IU Injection is used to improve blood sugar control in adults and children with type 1 and type 2 diabetes mellitus.
Dosage Form
Injection
Introduction
Biosulin N 40IU Injection is often prescribed along with short-acting insulin or other oral diabetes medicines. Your doctor or nurse will teach you the correct way of injecting it under the skin. Don’t stop taking it unless your doctor tells you to. It is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Check your blood sugar levels regularly, keep track of your results, and share them with your doctor. This is very important to work out the correct dose of the medicine for you.
Directions for Use
Your doctor or nurse will give you this medicine. Kindly do not self-administer.
Safety Information
Side Effects
Hypoglycemia (low blood sugar level), reactions at the injection site like redness or swelling, lipodystrophy (skin thickening or pits at the injection site), weight gain, edema (swelling over the whole body due to fluid retention)
Alcohol Warning
It is unsafe to consume alcohol with Biosulin N 40IU Injection.
Breastfeeding Warning
Biosulin N 40IU Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Pregnancy Warning
Biosulin N 40IU Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Interacting Medicines
Benazepril Captopril Enalapril Fosinopril
How it works
Biosulin N 40IU Injection is an intermediate-acting insulin that starts working in 1-2 hours after injection. It works similar to the insulin that is produced by the body. Insulin facilitates reuptake of sugar in muscle and fat cells and also suppresses the production of sugar in the liver. This helps to lower the blood sugar levels in diabetes mellitus.
Quick Tips
Hypoglycemia (low blood sugar level) is a common side effect. Hence regular monitoring of blood sugar levels is required while taking this medicine. Injection below the skin of the abdomen results in faster absorption than other injection sites. Injection sites must be rotated to prevent hard lumps from developing at one site. Opened vials/cartridge are good at room temperature for up to 4 weeks while unopened vials must be placed in the refrigerator (2°C–8°C).
Related Medicines
Huminsulin N 40IU/ml Injection
Humanext N 40IU/ml Injection
Recosulin N 40IU/ml Injection
Insugen-N 40IU/ml Injection
Iletin NPH 40IU/ml Injection
Longact 40IU/ml Injection
Insucare N 40IU/ml Injection
Frequently asked questions
How does biphasic isophane insulin work?
Insulin isophane is a recombinant human insulin analogue (genetically modified insulin grown in a laboratory and similar to human insulin). It's an intermediate acting insulin preparation. Insulin isophane works by replacing the normal production of insulin and helps transfer sugar from the blood into other body tissues, where it's used for energy generation. It also stops the liver from producing more sugar. Intermediate acting insulin preparations start working within an hour or two after injection and reach a peak activity period lasting up to seven hours, followed by a gradual decline; overall duration of action ranges from 18 to 24 hours.
What is Biosulin N 40IU Injection? How is it made?
Biosulin N 40IU Injection is a man-made version of human insulin produced using biotechnology called recombinant DNA technology. It's available as a sterile, aqueous, clear, and colorless solution containing insulin aspart along with other constituents like glycerin, phenol, metacresol, zinc, and sodium chloride etc.
Can Biosulin N 40IU Injection cause hypoglycemia? How do I prevent it?
Yes. Hypoglycemia is the most common side effect of Biosulin N 40IU Injection. This is more likely if you miss meals, drink alcohol, exercise intensely, or take other antidiabetic medications together with this injection. Therefore, try to maintain consistent meal timings and food intake. Snack as needed when exercising excessively. Regular monitoring of blood sugar levels is crucial. Always carry glucose tablets, honey, or fruit juice with you. Take all prescribed medication from your doctor on time and consult them if you experience any fluctuations in your blood sugar level.
What are the other side effects of Biosulin N 40IU Injection? How to prevent them?
Common side effects include injection site reactions such as redness, itching, pain, and swelling. These usually resolve on their own but can sometimes progress into lipodystrophy (abnormal fat tissue changes). This involves lipohypertrophy (thickening of adipose tissue) or lipoatrophy (thinning of adipose tissue), potentially impacting insulin absorption. Rotate your injection sites every week or two to minimize the risk of lipodystrophy. Avoid injecting in muscles or veins and use the same area for at least a week before moving to a new one.
How should Biosulin N 40IU Injection be used?
Biosulin N 40IU Injection is injected subcutaneously (under the skin). Your doctor will show you the injection site. Try not to use the same spot repeatedly. Rotate between your usual injection sites, such as abdomen, buttocks, upper legs, or upper arms. Never inject into a muscle or vein. Move to a new injection site every week or two. Inject in the same area of your body and ensure consistent movement within that region for one or two weeks before switching to another area. Follow your doctor's instructions for safe usage.
Is Biosulin N 40IU Injection given as an injection into a vein (intravenous)?
Yes, in certain cases like diabetic ketoacidosis and severe hyperglycemia, Biosulin N 40IU Injection might be administered intravenously by your doctor, under continuous blood sugar monitoring. However, this is only done within hospital settings.
Is Biosulin N 40IU Injection safe to use in pregnancy?
Yes, Biosulin N 40IU Injection is generally safe for use during pregnancy when prescribed and used properly by a qualified healthcare professional. However, it's important to inform your doctor if you are pregnant, planning a pregnancy, or breastfeeding before using this medication.
When does the dosage of Biosulin N 40IU Injection need to be changed?
You should consult your doctor about dose adjustments for weight changes (gain or loss), increased stress, illness, changes in diet such as missed meals, or alcohol consumption. Your dose might also change if you've started new exercise routines or are taking any other medications. Be mindful of potential side effects and any changes you experience while first using Biosulin N 40IU Injection.
