Apriglim-M 2 Tablet PR
Manufacturer
Aprica Pharmaceuticals Pvt Ltd
Salt Composition
Glimepiride (2mg) + Metformin (500mg)
Key Information
Short Description
Apriglim-M 2 Tablet PR is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Dosage Form
Tablet PR
Introduction
Apriglim-M 2 Tablet PR belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Directions for Use
Use it as advised by your doctor or check the label for directions before use. Apriglim-M 2 Tablet PR is to be taken with food.
Safety Information
Side Effects
Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea vomiting and stomach pain as Apriglim-M 2 Tablet PR may cause a rare but serious condition called lactic acidosis which is an excess of lactic acid in the blood.
Alcohol Warning
It is unsafe to consume alcohol with Apriglim-M 2 Tablet PR.
Breastfeeding Warning
Apriglim-M 2 Tablet PR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Pregnancy Warning
Apriglim-M 2 Tablet PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
How it works
Apriglim-M 2 Tablet PR is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.
Quick Tips
Take it with food to lower your chance of having an upset stomach. Monitor your blood sugar level regularly while you are taking this medicine. It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Apriglim-M 2 Tablet PR may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
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Frequently asked questions
What are the recommended storage conditions for Apriglim-M 2 Tablet PR?
Keep this medicine in its original container or package, tightly closed. Store it according to the instructions on the packaging label. Do not consume any unused medicine and make sure it is out of reach of pets, children, and others.
Can the use of Apriglim-M 2 Tablet PR lead to lactic acidosis?
Yes, the use of Apriglim-M 2 Tablet PR can lead to lactic acidosis. It is a medical emergency that occurs when lactic acid levels in the blood increase excessively. This condition, also known as MALA (Metformin-associated lactic acidosis), is a rare side effect of metformin use and can be harmful for people with underlying kidney disease, older adults, or those who consume large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling cold in the arms and legs, difficulty breathing, nausea, vomiting, stomach pain, or slow heart rate. If you experience any of these symptoms while taking Apriglim-M 2 Tablet PR, stop taking it and consult your doctor immediately.
What is Apriglim-M 2 Tablet PR?
Apglimm-M 2 Tablet PR combines two active ingredients: Glimepiride and Metformin. This medicine is used to treat type 2 diabetes mellitus (DM). It helps improve blood glucose levels in adults by working alongside a healthy diet and regular exercise. Glimepiride increases insulin release from the pancreas, while Metformin reduces glucose production in the liver and improves insulin sensitivity. This combination is not suitable for treating type 1 DM.
What are the possible side effects of Apriglim-M 2 Tablet PR?
Common side effects associated with Apriglim-M 2 Tablet PR include hypoglycemia (low blood sugar), altered taste, nausea, stomach pain, diarrhea, and headaches. It can also lead to serious but rare side effects such as lactic acidosis. Long-term use may increase the risk of vitamin B12 deficiency.
Can the use of Apriglim-M 2 Tablet PR cause Vitamin B12 deficiency?
Yes, long-term use of Apriglim-M 2 Tablet PR can lead to vitamin B12 deficiency. This is because it interferes with the absorption of vitamin B12 in the stomach. Untreated B12 deficiency may result in anemia and nerve problems such as tingling and numbness in hands and feet, weakness, urinary issues, changes in mental status, and difficulty maintaining balance (ataxia). To minimize these risks, some experts suggest taking vitamin B12 from external sources at least once a year.
Can the use of Apriglim-M 2 Tablet PR cause hypoglycemia?
Yes, the use of Apriglim-M 2 Tablet PR can lead to hypoglycemia (low blood sugar levels). Common symptoms include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. Hypoglycemia is more likely if you miss meals, drink alcohol, over-exercise, or take other antidiabetic medications along with Apriglim-M 2 Tablet PR. Regular monitoring of blood sugar levels is crucial to manage this potential side effect.
Is it safe to take alcohol while I am also taking Apriglim-M 2 Tablet PR?
No, consuming alcohol along with Apriglim-M 2 Tablet PR may increase your risk of hypoglycemia. It can also lead to a higher incidence of lactic acidosis. Therefore, it is essential to avoid alcoholic beverages while using this medication.