
Afadel 30 Tablet
Manufacturer
Adley Formulations
Salt Composition
Afatinib dimaleate (30mg)
Key Information
Short Description
Afadel 30 Tablet is used in the treatment of non-small cell lung cancer in adult patients with certain mutations of epidermal growth factor receptor (EGFR).
Dosage Form
Tablet
Introduction
Afadel 30 Tablet should be taken on an empty stomach but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Directions for Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Afadel 30 Tablet is to be taken empty stomach.
Safety Information
Side Effects
No common side effects listed.
Alcohol Warning
Consuming alcohol with Afadel 30 Tablet does not cause any harmful side effects.
Breastfeeding Warning
Afadel 30 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Pregnancy Warning
Afadel 30 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
How it works
Afadel 30 Tablet is an anti-cancer medication. It works by binding and inhibiting the enzyme receptors (EGFR, HER2, and HER4) that are responsible for the growth of cancer cells. Hence, resulting in the downregulation of signaling pathways. This is how it stops or slows the spread of cancer.
Quick Tips
You have been prescribed Afadel 30 Tablet for the treatment of certain type of lung cancer (non-small cell lung cancer). Take Afadel 30 Tablet on an empty stomach at least 1 hour before a meal or 2 hours after a meal. Diarrhea is common with Afadel 30 Tablet and may sometimes be severe. Your doctor may prescribe medicines to treat diarrhea. Stay hydrated and take this medicine exactly as directed. Afadel 30 Tablet can make your skin sensitive to the sun. Limit your time in the sun. Use sunscreen and wear protective clothing if you have to be in sunlight. Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it. Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting. Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.
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Frequently asked questions
Is Afadel 30 Tablet an immunotherapy or chemotherapy?
Afadel 30 Tablet is not immunotherapy nor conventional chemotherapy. It belongs to the class of kinase inhibitors used in anti-cancer medications. It works by blocking specific proteins involved in the growth and spread of cancer cells. By blocking these proteins, Afadel 30 Tablet inhibits the growth and multiplication of cancer cells.
How long does it take for Afadel 30 Tablet to work?
The peak concentrations of Afadel 30 Tablet are achieved within 2-5 hours after consumption. However, noticing a significant change in cancer progression might take weeks or months. Although symptom improvement may be observed, the effectiveness of Afadel 30 Tablet can only be confirmed after specific parameters have been determined.
How should I take Afadel 30 Tablet?
Afadel 30 Tablet is taken orally, without food, at least one hour before or three hours after meals. Swallow the complete tablet with water without crushing or breaking it. Take this medicine once daily around the same time each day to make remembering easier. If you find swallowing difficult, dissolve it in a glass of water. Do not use any other liquids instead of water. Drop the tablet into the water and stir occasionally for up to 15 minutes until it dissolves into very small particles before consuming.
Does Afadel 30 Tablet affect fertility?
Afadel 30 Tablet may decrease fertility in both men and women. Therefore, if you have concerns regarding fertility, consult your doctor who might recommend sperm or egg preservation before starting treatment.
Can Afadel 30 Tablet be used alongside chemotherapy?
There is no supporting evidence suggesting that Afadel 30 Tablet can be combined with other chemotherapy medicines. Afadel 30 Tablet is specifically designed for treating specific types of lung cancer after conventional chemotherapy has been ineffective.
Can Afadel 30 Tablet cure lung cancer?
No, Afadel 30 Tablet cannot cure lung cancer. However, it can significantly prolong survival and may reduce tumor size. It's important to remember that this medication is not a cure but helps manage the disease.
What should I avoid while taking Afadel 30 Tablet?
You should avoid prolonged sun exposure as Afadel 30 Tablet can make your skin more sensitive to sunlight. You may experience a severe sunburn or develop rashes, acne, or other skin complications. Therefore, always use sunscreen and wear a hat before going out in the sun. If you have to be outdoors, wear clothes that cover your skin.
What do I do if I experience diarrhea after taking Afadel 30 Tablet?
Diarrhea is a common side effect of Afadel 30 Tablet. If you experience severe diarrhea, which can lead to excessive fluid loss and kidney problems that could be life-threatening, start consuming plenty of fluids immediately and contact your doctor as soon as possible. Your doctor will initiate appropriate antidiarrheal treatment (e.g., loperamide) and may reduce the dosage or even discontinue treatment if you develop severe diarrhea.