Accurex Typhoid IgG/IgM Chromatographic Immunoassay

Short Description

Accurex Typhoid IgG/IgM Chromatographic Immunoassay is a lateral flow immunochromatographic assay for the simultaneous detection and differentiation of anti-Salmonella typhi (S. typhi) IgG and IgM in human whole blood/serum/plasma.

Dosage Form

Lateral flow immunoassay

Introduction

The Accurex Typhoid IgG/IgM Rapid Test is a lateral flow immunoassay for the simultaneous detection and differentiation of anti-Salmonella typhi (S. typhi) IgG and IgM in human whole blood/serum/plasma. It is intended to be used as a screening test and as an aid in the diagnosis of infection with S. typhi. Any reactive specimen with the Typhoid IgG/IgM Rapid Test must be confirmed with an alternative testing method(s).

Collect blood specimens into a lavender, blue or green top collection tube (containing EDTA, citrate or heparin, respectively in Vacutainer®) by veinpuncture. Separate the plasma by centrifugation. Carefully withdraw the plasma into new pre-labelled tube. For serum, collect blood specimen into a red top collection tube (containing no anticoagulants in Vacutainer®) by veinpuncture. Allow the blood to clot. Separate the serum by centrifugation. Carefully withdraw the serum into a new pre-labelled tube.

The test cassette consists of a pink-purple colored conjugate pad containing recombinant S. typhi H antigen and O antigen conjugated with colloid gold (Typhoid conjugates) and rabbit IgG-gold conjugates, a nitrocellulose membrane strip containing two test region (Test line M and G) and a control region (control line). When an adequate volume of test specimen is dispensed into the sample well of the cassette, the test specimen migrates by capillary action across the test cassette.